The Human T-Lymphotropic virus Type-I (HTLV), is a human RNA retrovirus that is known to cause adult T-cell leukemia and lymphoma. The HTLV-II virus shares approximately 70% genomic homology with HTLV-I. HTLV-II is found predominately in IV drug users and Native Americans, as well as Caribbean and South American Indian groups.
Many test methodologies are available worldwide for the serology of HTLV-I/II. The preferred method in the United States (U.S.) is use of an enzyme immunoassay (EIA) recommended by the FDA. EIAs are fast, efficient and allow for a quick turn-around-time for screening anti-HTLV-I/II.
The MP Diagnostics™ HTLV-I/II ELISA 4.0 is an enzyme-linked immunosorbent assay intended for the detection of antibodies to Human T-cell Lymphotropic Virus type 1 (HTLV-I) and type 2 (HTLV-II) in human serum or plasma. It is intended as a screening test, requiring repeat testing of initially reactive specimens.
The MP Diagnostics™ HTLV Blot 2.4 is a qualitative enzyme immunoassay for the in vitro detection of antibodies to HTLV-I and HTLV-II in human serum or plasma. It is intended for use as a more specific supplemental test on human serum or plasma specimens found repeatedly reactive using screening procedures like the Enzyme-Linked Immunosorbent Assays (ELISA).
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